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'Locked' cancer therapeutic activates in tumors, limiting off-target exposure in mice
'Locked' cancer therapeutic activates in tumors, limiting off-target exposure in mice
Although there are many cancer treatments available today that effectively eliminate abnormal cells, these therapies may also damage healthy cells, leading to unwanted side effects.
EU's race for lithium and rare earths sidelined calls to reduce consumption, finds study
EU's race for lithium and rare earths sidelined calls to reduce consumption, finds study
In 2024, the Critical Raw Materials Act (CRMA) came into force. The regulation is intended to secure Europe's supply of critical raw materials, especially minerals and metals such as lithium, cobalt, and rare earth elements. The EU is therefore focusing on reducing its dependence
We’re going to party like it’s 1629… the masques, the music and the mayhem of Banqueting H
We’re going to party like it’s 1629… the masques, the music and the mayhem of Banqueting H
What music soundtracked 17th-century England? Ahead of a DJ set in Banqueting House, Georgia Mann looks at the wild, the experimental, the melancholic – and why a theorbo caused a security alertKing Charles is on the throne, there’s anxiety around the power-brokers of Whitehall,
Traitors’ Stephen Libby on fashion: need some thrifty tailoring? Try your local dry cleane
Traitors’ Stephen Libby on fashion: need some thrifty tailoring? Try your local dry cleane
Alterations that don’t cost a fortune can transform old trousers, jackets or shirts into bespoke piecesWhen I started shopping in vintage stores, I fell into the trap of thinking that if something wasn’t in my size there was nothing to be done. I’d still buy beautiful shirts that
Most patients with obesity don't get the weight counseling they need, say researchers
Most patients with obesity don't get the weight counseling they need, say researchers
There's no shortage of weight-loss advice on social media, TikTok, television and AI chatbots. But the most credible source—a patient's own primary care doctor—is often the one they're not hearing from.
Steal This Story, Please! review – Amy Goodman, stalwart of the American left, shows her t
Steal This Story, Please! review – Amy Goodman, stalwart of the American left, shows her t
This comprehensive documentary about the Democracy Now! radio show host and seasoned investigative reporter takes in a massacre in East Timor, the actions of oil giants and a flustered Bill Clinton as it reflects her vital workBefore there was Michael Moore, there was campaigning
Saudi Pro League tries to move on from era of ageing megastar but big names still loom
Saudi Pro League tries to move on from era of ageing megastar but big names still loom
As Ronaldo heads towards 1,000 career-goals, league plans to lift standard of Saudi Arabian football, not just the clubsThere’s no Mohamed Salah in the new Saudi Pro League season that kicks off on Thursday and while the age of the ageing megastar is ending, there is still the st
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Eerie silence and ‘still surviving’: what happened next after steel town’s last blast furnace shut down
Exhibition in Port Talbot is part of project exploring how communities experience endings and transitionsMargaret Heggett, 95, does not remember a time when Port Talbot was ever quiet. Born and raised in the shadow of the steelworks, with a father, brother and husband who worked there, she never imagined what the town could look or sound like without its blast furnaces.“I’m not saying it was beautiful, but there were jobs. We did know the closure was coming and we have to move with the
Climate debate remains dominated by established voices despite social media, research find
Climate debate remains dominated by established voices despite social media, research find
When social media arrived on the scene, there were high hopes that they would improve—or even "democratize"—communication about climate change by, for instance, lowering access barriers, creating a more direct channel between science and the public, and giving more voices from ci
Miscarriages triple, healthcare access worsens… the nightmare for pregnant women in Gaza
Miscarriages triple, healthcare access worsens… the nightmare for pregnant women in Gaza
With over 3,950 cases recorded by the ministry of health in Gaza, the number of miscarriages between January and June has tripled compared with the previous six months. During this period, there was approximately one miscarriage for every five live births. The Observers team spok
Don’t despair about what’s happening to our planet. That’s what they want you to feel
Don’t despair about what’s happening to our planet. That’s what they want you to feel
There are social tipping points when the seemingly impossible suddenly becomes inevitable. Good journalism plays an essential role in helping drive these shifts and shows us how real change can happenClimate campaign 2026: help us reach 20,000 acts of supportThere are many reason
These Shades Are Cause For Late-Summer Lens Envy
These Shades Are Cause For Late-Summer Lens Envy
From barely-there frames to oversized statement shades, explore the sunglasses worth knowing this August, handpicked from Mytheresa’s eyewear offering.